Tramadol is a painkiller, also known as an analgesic, that is prescribed to treat the symptoms of moderate to severe pain. It is most known under the brand name Ultram, and is available either via prescription from a doctor, or online pharmacies. It belongs to a group of painkillers called opioids, which act upon opioid receptors to generate morphine-like effects, which work quickly and effectively to stop pain in its tracks. It is known in the scientific community as one of the most useful drugs amongst the opioids, due to its unique mechanism of action and effectiveness, which has led it to be successfully used in a wide range of applications, for different types of pain. In addition, when compared to typical opioids such as morphine, it is rarely known to cause respiratory depression or Tramadol addiction, something that other opioids are known for.
This medication was developed in Germany by Grunenthal, a German pharmaceutical company that describes itself as a 'global leader in pain management and related diseases'. Founded in 1946, Grunenthal is a family-owned company which now employs over 4,500 people. Currently over 50% of the profits it earns come from analgesics such as Tramadol HCL. Its most popular medication, it was discovered by Grunenthal in 1961, entered the West German market in 1977, the Polish market in 1992, the United States market in 1995 and the United Kingdom market in 1997. It is currently the 25th most prescribed medication in the United States, with almost 25 million prescriptions issued per year.
Although the Food and Drug Association (FDA) approved the drug for use in 1995, the patent was ruled invalid in 2009, which is 5 years prior to when the patent was due to expire in 2014. Due to this, Tramadol generic versions have been developed there since that point. This is seen as a positive thing for the pharmaceutical market, as it drives the price down for consumers, since Tramadol generic versions can then be made without having to account for the costs that accrued during the development and marketing phase. Additionally, further competitors entering the market ensures that the different manufacturers must convince the public to buy their brand over other brands, by keeping the price as low as possible.
Tramadol uses vary, as this medication can be used for a vast array of conditions. Principally however, it is used for the treatment of pain. Miriam Webster dictionary defines pain as:
As suggested above, there is more than one type of pain, and further to this, there is more than one type of use of Tramadol for pain. Some of the most common conditions that this medication is used for are as follows:
As can be seen from the above list, there is a huge variety of applications for this medication, which is why so many people try to buy Tramadol online.
If you are looking to buy Tramadol in the UK, you may first wish to know exactly how it works. In the simplest way possible, it works by changing how our body feels pain. Once taken, it works in a similar way to other opioids, by binding to receptors in our brain and spinal cord that work by blocking pain. This is the same method that endorphins in the body use. Once they have bound to these receptors, which are located on nerve endings, the messages that travel through our body telling us that we are experiencing pain are inhibited. In addition to this, studies have shown that it can also affect the same brain chemicals that anti-depressants effect, serotonin, and norepinephrine, which can further relieve unpleasant pain sensations.
How long this medication lasts depends on the amount of medication and type of Tramadol pill that is taken. There are two different versions of this medication, the normal version, and the extended release.
After normal Tramadol 100 mg is taken, it is absorbed into the intestine, begins to work within 30 to 60 minutes. After around 2 hours, the peak concentration of this medication in the body is achieved. The half-life of this medication is between 5 to 6 hours, which is the same point that the pain-relieving effects start to diminish. If you take a lesser amount of this medication, for example Tramadol 50 mg, then the effects may not last as long, and will not be as powerful.
The extended-release version slowly releases the medication over a period instead. With the extended-release version, the medication takes a lot longer to peak, between 10 and 12 hours. However, the effect of the drug lasts a lot longer, generally around 24 hours. This type is prescribed for long-term pain.
In addition, like with any medication, it can depend on several other factors how long the effects of this medication take to kick in, and how long they last. For example, older people process this medication more slowly, and are more likely to be taking other medications too, which could also slow the absorption of this medication. Other factors that can influence how long it lasts is your weight, as people who weigh more may need more of the medication for it to take effect, and your gender, as studies have found that women are more likely to experience stronger effects for longer, than men.
It is important when taking any medication that you follow the manufacturers dosage instructions first, and this is the same when considering what Tramadol dosage to take. For the normal version of this medication, it is recommended that you start on a dose of Tramadol HCL 50 mg and proceed to increase the dosage from there if needed. At this dosage it can be taken every 4 to 6 hours as needed, up to a maximum dose of 400 mg per day.
For the extended-release version, only one tablet is taken per day, as the effects last for 24 hours. This is available in doses of 100 mg, 200 mg and 300 mg. The recommended maximum dose for this version of the medication is 300 mg per day.
When taking either of these tablets, they should be swallowed whole with a glass of water. They should not be chewed, crushed, or dissolved. It does not matter whether this medication is taken with or without food, as food does not impact the effects of it. If you are older, or have kidney or liver disease, a lower dose of this medication should be taken than usual.
It is important that you do not take more than the maximum dose of either of these types of medication, as this can increase the risk of side effects.
Like anytime you buy painkillers, there are always going to be side effects that could potentially occur. Fortunately, the incidence of Tramadol side effects is low, with the most common ones only affecting around 5% of those that take it. If you are concerned about side effects, you should take the lowest dose and buy Tramadol 50 mg, as opposed to Tramadol 100 mg. This will reduce the risk of side effects occurring.
The following is a list of some of these side effects. For a full list you should always conduct your own research.
Occasionally people may experience an allergic reaction to taking this medication. If this occurs, you should seek immediate medical assistance.
Tramadol pills are approved by the Food and Drug Association (FDA) in the United States and the Medicines and Healthcare products Regulatory Agency (MHRA) in the United Kingdom for the treatment of pain. If certain rules are followed, this medication is safe to be taken by anyone. Firstly, it is important that you do not drink alcohol when taking this medication, as the combination of Tramadol and alcohol can increase the risk of side effects. Additionally, before taking this medication, you should always consult with a medical professional. This is because Tramadol interactions can occur with other medications that you may already be taking, and the two may interfere with each other and reduce their effectiveness, or potentially be a dangerous mix.
For any other Tramadol warnings, and whether you can take this medication alongside any pre-existing conditions, you should always consult the manufacturer's instructions, or alternatively speak with your local doctor.
When comparing Tramadol to Codeine, there are undoubtedly some similarities, however there are also many differences. They are both opiates, but Codeine is made from the poppy plant, whereas Tramadol HCL is similar, but is synthesized in a laboratory. As a result, it has been engineered to be less addictive, which therefore reduces the risk of Tramadol withdrawal if stopped abruptly. Additionally, when taking a dose such as Tramadol HCL 50 mg, it can be used in many different applications and does not interact with nearly as many other medications as Codeine, which cannot be taken under a wider array of circumstances. Finally, studies have found that there is a lower occurrence of side effects when taking Tramadol 50 mg, than when taking the equivalent dose of Codeine.
Before you buy Tramadol online you should look for alternative methods of dealing with pain, without the need to try to find painkillers in the UK. It can be expensive to take medications over a long period of time, which makes it preferable to try to do without medication initially. Some of the methods that some people recommend are:
Of course, if you have tried these and they have not worked, or you do not wish to waste further time, then there are ways that you can buy Tramadol online in the UK.
So, after reading the above information, if you are sure that you want to buy Tramadol 50 mg, or other dosages or similar medications, then look no further. Our online pharmacy stocks a vast array of different medications for all your needs. If you are interested in having medication delivered to your door in the UK quickly and discreetly, then visit www.buysleepingpills.com to view our complete product range.
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Info Reviewed: 06 September 2022
Next Review Due: September 2023
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