Pregabalin is a multi-purpose gabapentinoid medication that is used for a variety of conditions. It has anti-convulsant, anti-anxiety and analgesic properties and is used as a painkiller, anxiety medication and seizure drug. Due to its wide array of applications, it is widely regarded as one of the best-known medications available. The Pregabalin brand name is Lyrica, which is the name that people most associate with it. Under this brand name, it is available either on prescription from a doctor or via online pharmacies, such as ours.
Gabapentinoids were first approved for medical use in the 1990s, and quickly became extremely popular. Pregabalin itself was invented by medicinal chemist Richard Bruce Silverman at Northwestern University and approved for use in the United Kingdom by the Medicines and Healthcare products Regulatory Agency in 2004, and in the United States by the Food and Drug Association in 2005. It is now the 70th most prescribed medication in the United States, with over 11 million prescriptions per year.
It is now also available as a Pregabalin generic version, as the patent expired in relation to its use in treating epilepsy and generalized anxiety disorder in July 2014 and expired in its use for neuropathic pain in July 2017. This Pregabalin generic version is clinically the same as the branded version, however it is sold at much cheaper prices. This can be done as the pharmaceutical companies that manufacture the generic version have not had to spend money on manufacturing and commercial costs, so the savings can be passed directly onto the consumer.
This medication is used for a variety of conditions. As previously mentioned, some Pregabalin uses are for pain, specifically neuropathic pain (nerve related pain), anxiety and seizures.
When referring to neuropathic pain, people are often referring to damage to the peripheral nervous system, which is the network of nerves aside from those located in the brain or spinal cord. This system communicates with the central nervous system, the spine and brain, telling it what sensations we feel. It is commonly described as a burning, tingling, or stabbing sensation.
There are several conditions that can cause neuropathic pain. Some of the more common ones are:
This medication can also be used to treat seizures, from conditions such as epilepsy. Epilepsy is when sudden bursts of electrical activity in the brain causes seizures. It can be a hereditary condition, passed down through family, or as a result of a severe head injury. Studies have found that when used in conjunction with other seizure medications, it can cause a large reduction in seizures, for some people over 50%.
In addition to the above, there are other Pregabalin uses. It can also be prescribed to treat anxiety related conditions. Anxiety is a feeling of exaggerated fear or unease that can occur at any time. Some of the symptoms of anxiety are:
There is not only one type of anxiety, however. There are several conditions which are caused by anxiety, and these differ depending on when the anxiety becomes apparent. Some of these are:
Out of the above anxiety disorders, this medication is mainly prescribed for GAD.
This medication works by altering electrical activity in the brain and inhibiting neurotransmitters, to reduce the signals that are being sent along the central nervous system. Neurotransmitters send messages between our nerve cells. When these neurotransmitters are inhibited, less messages are sent out. With all the conditions that this medication is used to treat, this works effectively by helping to reduce seizures, limit our sensation of pain and calm the central nervous system to prevent anxiety symptoms.
It does this in distinct ways. With epilepsy it calms the abnormal electrical signals in the brain to reduce seizures. With anxiety it stops our brains from releasing chemicals that make us anxious. With nerve pain it interferes with the messages being sent along the spine that inform us we are feeling pain.
This depends on the condition that the medication is being used for. If you buy Pregabalin for anxiety, it can take up to four weeks for the medication to start working, although some people report that it starts working for them after a week or so. This is unusual as typically anti-anxiety medications work instantly, however this medication has shown similar levels of effectiveness when taken over the long-term in comparison to benzodiazepines, with less risk of Pregabalin withdrawal when ceasing to take it. When treating pain and seizures, it is recommended that this medication is taken for at least one to two weeks before effects will start to show, although some people do experience benefits from taking the medication almost immediately.
This medication stays in the body for around 35 hours, before it leaves the body entirely, although the effects of the medication may disappear quicker than this. Further to this, studies have found that it is present and detectable in urine for 5-6 days after consumption. The half-life, which is how long it takes for the level of medication in the body to be halved, is roughly 6.3 hours.
How long the medication lasts also depends on how quickly it is metabolised in the body. There are various factors that can determine how quickly a medication is processed. People who weigh more, people who take their medication alongside a large or fatty meal, those with liver or kidney conditions, and older generations tend to process medications more slowly. Conversely, people in the CYP450 gene group and people who are underweight process medications quicker.
Before you buy Pregabalin online, you should inform yourself on what Pregabalin dose you should be taking.
If you are taking this medication for seizures, you should start on a low dose of Pregabalin 75 mg, which should then be increased in 7-day intervals if needed, up to a maximum dose of Pregabalin 300 mg taken twice per day.
When taken for neuropathic pain and anxiety, you should start on a dose of Pregabalin 150 mg, which should then be increased in 7-day intervals, up to a maximum dose of Pregabalin 300 mg taken twice per day. If you are elderly or suffer from liver or kidney disease, your doctor may recommend that you start on a lower dose of Pregabalin 100 mg instead, due to the increased risk of side effects.
Regardless of the dose, you should ensure that you take this medication correctly, by swallowing the medication whole with a glass of water. It should not be chewed or dissolved. It can be taken with or without food but should be taken in a consistent manner - if you normally take it with food, you should always take it with food. After you take this medication, it should become effective within an hour or so.
Fortunately for those looking to buy Pregabalin online in the UK, there is a low incidence of those who take this medication suffering from Pregabalin side effects. That is because any side effects that do occur are rare and uncommon. It is said that side effects occur when taking this medication in roughly 1 in 100 people. Some of these side effects are:
It is important that you do not take more than the maximum dose, as this can increase the risk of side effects. Very occasionally, people may experience an allergic reaction to this medication. If this is the case, you should seek immediate medical attention.
This medication is extremely well tolerated, but just like any time you buy painkillers, you should double-check that you do not belong to a group that may be more seriously affected by this medication than others. Some people who should pay extra attention to Pregabalin warnings are:
It is easy to compare Pregabalin vs Gabapentin, as these are both such similar medications. There are however some differences. Although they are both seizure medications that can be used to treat neuropathic pain, Pregabalin works faster than Gabapentin, becoming effective within an hour, whereas Gabapentin takes between 3 and 4 hours to reach peak concentration.
Studies have found that a dose of Pregabalin 300 mg is more effective at treating neuropathic pain than the same dose of Gabapentin, which is why people often try to buy Pregabalin in the UK when they are looking online for painkillers in the UK.
Regardless of the above, some medications will work better for some, whereas other medications will work better for others. It is down to personal preference.
Before you buy Pregabalin online, you should consider whether this is the best medication for your condition. Although it is useful for a variety of conditions, it is not typically the first line treatment for anxiety for example. However, it is a useful option, as it can be taken long-term. So, for long-term anxiety issues, where benzodiazepines are not suitable due to their addictive nature, it may be best to buy Pregabalin instead.
Additionally, it has been shown that certain alternative methods can be useful in helping to treat pain before taking medication, such as:
You should try at least one of these prior to taking this medication.
Neuropathic pain is a pain condition which is chronic, commonly known as long-term, and caused by injury or damage to the nerves that transfer information throughout the body. Often symptoms can improve as the underlying condition itself is treated.
To find relief for this problem you can now buy Pregabalin online in the UK. We offer the cheapest, most reliable way to buy pregabalin in the UK anywhere on the internet. If you are interested in discreet delivery directly to your door and are considering buying medication to help to treat your condition, you can visit www.buysleepingpills.com to view our complete product range. Our helpful team are available 24/7 to assist you with any queries that you may have.
Info Reviewed: 06 September 2022
Next Review Due: September 2023
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